Publications & media

Selected discoveries.

A curated selection, each entry with a DOI or PubMed reference. The complete record is held on PubMed (260+ publications, as of 2026).

2025. Publications

Original ArticleCancer Cell

Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses

Ren L, Liu C, Çifcibaşı K, … Demir IE

DOI PubMed

Original ArticleCancer Letters

Pancreatic cancer cells survive in the neural niche during neoadjuvant therapy

Çifcibaşı K, Goess R, Munkhbaatar E, … Mota Reyes C

DOI PubMed

Original ArticleBritish Journal of Cancer

Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration

Wong FC, Merker SR, Bauer L, … Kahlert C

DOI PubMed

Original ArticleNeoplasia

Pancreatic cancer cells infiltrate nerves through TGFbeta1-driven perineural epithelial-to-mesenchymal-like transdifferentiation

Krauss T, Gürcinar IH, Bourquain U, … Safak O

DOI PubMed

Original ArticleSurgery

Neural invasion severity is a strong predictor of local recurrence in pancreatic ductal adenocarcinoma

Schorn S, Fritz A, Kaissis G, … Ceyhan GO

DOI PubMed

CommentThe Lancet Regional Health – Europe

Economic pressures threaten surgical quality in Germany: immediate policy action required

Schorn S, Friess H, Demir IE

DOI PubMed

Original ArticlePancreatology

A porcine model of acute necrotizing pancreatitis

Steiner JM, Algül H, Ruess DA, … Steiger K

DOI PubMed

2023. Publications

Original ArticleJournal of Clinical Investigation

Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion

Wang X, Istvanffy R, Ye L, … Demir IE

DOI PubMed

2021. Publications

CommentNature Reviews Gastroenterology & Hepatology

Chemokines: the (un)usual suspects in pancreatic cancer neural invasion

Demir IE, Mota Reyes C

DOI PubMed

2020. Publications

Original ArticleClinical Cancer Research

Neoadjuvant Therapy Remodels the Pancreatic Cancer Microenvironment via Depletion of Protumorigenic Immune Cells

Mota Reyes C, Teller S, Muckenhuber A, … Demir IE

DOI PubMed

2017. Publications

ReviewSurgical Oncology

The influence of neural invasion on survival and tumor recurrence in pancreatic ductal adenocarcinoma — a systematic review and meta-analysis

Schorn S, Demir IE, Haller B, … Ceyhan GO

DOI PubMed

Original ArticleProceedings of the National Academy of Sciences (PNAS)

Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells

Demir IE, Kujundzic K, Pfitzinger PL, … Ceyhan GO

DOI PubMed

2015. Publications

ReviewNature Reviews Gastroenterology & Hepatology

Neural plasticity in pancreatitis and pancreatic cancer

Demir IE, Friess H, Ceyhan GO

DOI PubMed

2014. Publications

Original ArticleJournal of the National Cancer Institute

Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion

Demir IE, Boldis A, Pfitzinger PL, … Ceyhan GO

DOI PubMed

2011. Publications

DissertationTU Munich — doctoral thesis, summa cum laude

Neural remodeling and neuronal plasticity in pancreatic cancer and chronic pancreatitis

Demir IE · Doktorvater: Univ.-Prof. Dr. H. Friess

2009. Publications

Original ArticleGastroenterology

Pancreatic neuropathy and neuropathic pain — a comprehensive pathomorphological study of 546 cases

Ceyhan GO, Bergmann F, Kadihasanoglu M, … Friess H

DOI PubMed

Media

Coverage and interviews

TUM Pressemitteilung

Profiles

Complete publication records

PubMed TUM Department of Surgery Research group at TUM

2025. Publications

Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses

Pancreatic cancer cells survive in the neural niche during neoadjuvant therapy

Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration

Pancreatic cancer cells infiltrate nerves through TGFbeta1-driven perineural epithelial-to-mesenchymal-like transdifferentiation

Neural invasion severity is a strong predictor of local recurrence in pancreatic ductal adenocarcinoma

Economic pressures threaten surgical quality in Germany: immediate policy action required

A porcine model of acute necrotizing pancreatitis

2023. Publications

Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion

2021. Publications

Chemokines: the (un)usual suspects in pancreatic cancer neural invasion

2020. Publications

Neoadjuvant Therapy Remodels the Pancreatic Cancer Microenvironment via Depletion of Protumorigenic Immune Cells

2017. Publications

The influence of neural invasion on survival and tumor recurrence in pancreatic ductal adenocarcinoma — a systematic review and meta-analysis

Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells

2015. Publications

Neural plasticity in pancreatitis and pancreatic cancer

2014. Publications

Investigation of Schwann cells at neoplastic cell sites before the onset of cancer invasion

2011. Publications

Neural remodeling and neuronal plasticity in pancreatic cancer and chronic pancreatitis

2009. Publications

Pancreatic neuropathy and neuropathic pain — a comprehensive pathomorphological study of 546 cases

Six ERC Consolidator Grants for TUM researchers

ERC Consolidator Grant für Prof. Ekin Demir

Nachgefragt: Was macht eigentlich Prof. Dr. Ihsan Ekin Demir?

Rising Star am Rechts der Isar — Interview